王欢

作者: 时间:2024-04-24 点击数:

 

 

教师基本信息:

姓名  王欢

职称  副教授

电子邮箱karl2wanghuan@163.com

办公地点大连大学问源楼B3

个人简介:

 

2008-2012年就读于日本京都大学医学院获博士学位,2012-2014在浙江大学药学院从事博士后研究2015年加入大连大学生命健康学院。曾作为负责人承担国家自然基金青年基金及面上项目等课题。

 

研究方向:

 

主要从事围绕脑缺血,脓毒性脑病等心脑血管疾病及神经系统疾病,开展基于脑血管生物学及脑微循环功能障碍的神经系统疾病发病机制研究。

 

代表性论文和专著:

1. Jiang Y, Lin Y, Tan Y, Shen X, Liao M, Wang H, Lu N, Han F, Xu N, Tang C, Song J, Tao R. Electroacupuncture ameliorates cerebrovascular impairment in Alzheimer's disease mice via melatonin signaling. CNS Neurosci Ther. 2023 Mar;29(3):917-931. doi: 10.1111/cns.14027. Epub 2022 Nov 15.

2. Tang C, Jin Y, Wang H. The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy. Front Synaptic Neurosci. 2022 Dec 2;14:1054605. doi: 10.3389/fnsyn.2022.1054605.

3. Tao R, Wang N, Shen T, Tan Y, Ren Y, Wei W, Liao M, Tan D, Tang C, Xu N, Wang H, Liu X, Li X. High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease. Theranostics. 2022 Feb 28;12(6):2549-2559.

4. Tao R, Liao M, Wang Y, Wang H, Tan Y, Qin S, Wei W, Tang C, Liang X, Han Y, Li X. In Situ Imaging of Formaldehyde in Live Mice with High Spatiotemporal Resolution Reveals Aldehyde Dehydrogenase-2 as a Potential Target for Alzheimer's Disease Treatment. Anal Chem. 2022 Jan 18;94(2):1308-1317.

5. Wang H, Yin YX, Gong DM, Hong LJ, Wu G, Jiang Q, Wang CK, Blinder P, Long S, Han F, Lu YM. Cathepsin B inhibition ameliorates leukocyte-endothelial adhesion in the BTBR mouse model of autism. CNS Neurosci Ther. 2019 Apr;25(4):476-485.