一、教师基本信息：

姓名：肖栋梁

职称：讲师

电子邮箱：xdl120318@163.com

xiaodongliang@dlu.edu.cn

办公地点：大连大学生命健康学院问源楼A座3楼

二、个人简介：

男，博士，讲师。

2011-2015，大连大学生命科学与技术学院，学士

2015-2018，沈阳药科大学中药学院，硕士

2018-2022，中国农业科学院生物技术研究所，博士

2022年11月-至今，大连大学生命健康学院，讲师

主持辽宁省教育厅基本科研项目1项，参与国家自然科学基金面上项目2项。在Proc. Natl. Acad. Sci. U.S.A.、J. Nat. Prod等国际权威期刊上发表SCI论文7篇 。担任J. Pept. Sci.等期刊特约审稿人。

三、研究方向：

主要从事微生物活性次级代谢产物的高效挖掘和生物合成研究，主要内容包括：

（1）基于基因组学、代谢组学联合分析的功能基因挖掘和活性产物分离鉴定。

（2）微生物活性次级代谢产物的生物合成途径解析。

四、代表性论文：

[1] Chen Wang^#, Dongliang Xiao^#, Baoqing Dun^#, Miaomiao Yin, Adigo Setargie Tsega, Linan Xie, Wenhua Li, Qun Yue, Sibao Wang, Han Gao, Min Lin, Liwen Zhang, István Molnár, Yuquan Xu. Chemometrics and genome mining reveal an unprecedented family of sugar acid–containing fungal nonribosomal cyclodepsipeptides, Proceedings of the National Academy of Sciences of the United

States of America, 2022, 119(32): e2123379119 (IF=11.3, JCR 1区)

[2] Dongliang Xiao^#, Wenhua Li^#, Tianyi Li^#, Jianshuang Zhou, Mei Zhang, Xinqi Chen, Liwen Zhang, Qun Yue, Baoqing Dun, Chen Wang, Yuquan Xu. Mass Spectrometry-Guided Discovery of Multi-N-Methylated Cyclodecapeptides Auyuittuqamides E–H from Sesquicillium sp. QL0466, Journal of Natural Products, 2023, 86(5): 1240-1250 (IF=5.1, JCR 1区)

[3] Dongliang Xiao, Mei Zhang, Ping Wu, Tianyi Li, Wenhua Li, Liwen Zhang, Qun Yue, Xinqi Chen, Xiaoyi Wei, Yuquan Xu, Chen Wang. Halovirs I–K, antibacterial and cytotoxic lipopeptaibols from the plant pathogenic fungus Paramyrothecium roridum NRRL 2183, The Journal of Antibiotics, 2022, 75(5): 247-257 (IF=3.3, JCR 2区)

[4] Linan Xie^#, Dongliang Xiao^#, Wang Xiaojing^#, Chen Wang, Jing Bai, Qun Yue, Haitao Yue, Ye Li, István Molnár, Yuquan Xu, Liwen Zhang. Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1, mSphere, 2020, 5(6): e00949-20 (IF=3.3, JCR 2区)

[5] Miaomiao Yin, Dongliang Xiao, Chen Wang, Liwen Zhang, Baoqing Dun, Qun Yue. The regulation of BbLaeA on the production of beauvericin and bassiatin in Beauveria bassiana. World Journal of Microbiology and Biotechnology, 2021, 38(1): 1 (IF=4.1, JCR 2区)

[6] Dongliang Xiao^#, Yan Wang^#, Congcong Gao, Xuemei Zhang, Weixing Feng, Xuan Lu, Baomin Feng. A New Quinazolinone Alkaloid along with Known Compounds with Seed-Germination-Promoting Activity from Rhodiola tibetica Endophytic Fungus Penicillium sp. HJT-A-6, Molecules, 2024, 29(9), 2112 (IF=4.6, JCR 2区)

[7] Dongliang Xiao^#, Xiaobao Li^#, Xuemei Zhang, Nan Jiang, Dun-Zhu Luosang, Weixing Feng, Xuan Lu, Baomin Feng, Two new secondary metabolites polyketides from Rhodiola tibetica endophytic fungus Penicillium sp. HJT-A-6, Chinese Herbal Medicines, 2024, Accepted (IF=3.8)